I started out using PowerPoint, and it was good. I perfected the six slide presentation. I discovered Prezi, and it was... interesting. I like the idea of a non-linear presentation which focuses in and out and slides around to make its point. And I like being able to quickly make a presentation that tells a compelling story without having to move from left to right.
And then, to quote Upworthy, I found the Sozi plugin for Inkscape, and it blew my mind.
So okay, you need to be handy with vector graphics (SVG) if you want to make a professional looking poster using Inkscape. And you have to be careful, I discovered, about using free-flowing text, which just plain doesn't show up in Sozi. But, it's easy to find nice examples of people who have already made professional looking posters using Inkscape, and it's easy to "Convert to Text" to fix free-flowing text, and it is so easy to use the Sozi plugin to sequence frames and create an amazing looking presentation that will impress your boss.
But more than this, I have recently discovered that you can use Inkscape to embed links - internal and external - within an SVG document, so really, as far as I can tell, there are two kinds of websites you should be thinking about: One built on the idea of application, as in single page application, or server-side templated application or whatever, but definitely HTML5; and one built on the idea of presentation. And for a presentation website, why not just use SVG, using Inkscape and Sozi as a development tool? Really. Why not?